马刚教授

马刚，男，九三学社社员。教授，博士生导师。博士研究生学历，博士学位。1996年至1999年在北京大学化学与分子工程学院吴瑾光教授课题组攻读博士学位。2000年至2008年，在美国俄亥俄州立大学化学系Heather C. Allen教授课题组任博士后及助理研究员。2008年至2010年在美国耶鲁大学化学系Elsa C. Y. Yan教授课题组任副研究员。2010年来到河北大学工作。在美期间主要应用和频振动光谱 (Sum Frequency Generation Vibrational Spectroscopy) 技术研究生物膜结构、蛋白错误折叠、以及与环境分子科学相关的界面过程。目前主要应用和频振动光谱、红外光谱、红外光谱探针、拉曼光谱、荧光光谱、原子力显微镜等多种物理化学手段研究淀粉样多肽自组装结构并探索相关应用。从事科研工作以来，在包括 J. Am. Chem. Soc.、J. Phys. Chem. B、Langmuir、PCCP 等国内外知名刊物上发表论文四十余篇，总引用次数1700余次。主持国家自然科学基金和省部级项目多项。作为第一完成人获2019年度河北省自然科学三等奖一项。获奖成果为《振动光谱在分子结构研究中的应用》。

Prof. Gang Ma obtained his Ph.D. in Chemistry from Peking University in 1999. From May 2000 to January 2008, he was a postdoctoral researcher and then research associate in the group of Prof. Heather C. Allen in the Department of Chemistry at The Ohio State University. From February 2008 to January 2010, he was an associate research scientist in the group of Prof. Elsa C. Y. Yan in the Department of Chemistry at Yale University. Gang Ma joined the faculty at Hebei University in 2010 and he is currently a full professor of chemistry in the College of Chemistry and Environmental Science. Research in Prof. Ma’s group focuses on using sum frequency generation vibrational spectroscopy, FTIR spectroscopy, IR probe technique, Raman spectroscopy, and AFM to study amyloid peptide self-assembly and exploring potential applications of amyloid assembly.

E-mail: gangma@hbu.edu.cn

Recent Publications (*Corresponding Author):
 1.      Yao Wang; Baohuan Jia; Min You; Haoran Fan; Siyu Cao; Hui Li; Wenkai Zhang*; Gang Ma*, Modulation of Surface-Catalyzed Secondary Nucleation During Amyloid Fibrillation of Hen Egg White Lysozyme by Two Common Surfactants, Journal of Physical Chemistry B, 2019, 123 (29): 6200-6211.
2.      Lujuan Yang; Haoyi Li*; Linxia Yao; Yang Yu; Gang Ma*, Amyloid-Based Injectable Hydrogel Derived from Hydrolyzed Hen Egg White Lysozyme, ACS Omega, 2019, 4 (5): 8071-8080.
3.      Liangliang Cui; Sujuan Wang*; Jian Zhang; Mengna Wang; Yan Gao; Libin Bai; Hailei Zhang; Gang Ma*; Xinwu Ba*, Effect of Curcumin Derivatives on Hen Egg White Lysozyme Amyloid Fibrillation and Their Interaction Study by Spectroscopic Methods, Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy, 2019, 223: 117365-117365.
4.      Sujuan Wang; Xixi Peng; Liangliang Cui; Tongtong Li; Bei Yu; Gang Ma*; Xinwu Ba*, Synthesis of Water-Soluble Curcumin Derivatives and Their Inhibition on Lysozyme Amyloid Fibrillation, Spectrochimica Acta Part A-Molecular and Biomolecular Spectroscopy, 2018, 190: 89-95.
5.      Wenli Tian; Dan Wang; Haoran Fan; Lujuan Yang; Gang Ma*, A Plasma Biochemical Analysis of Acute Lead Poisoning in a Rat Model by Chemometrics-Based Fourier Transform Infrared Spectroscopy: An Exploratory Study, Frontiers in Chemistry, 2018, 6: 261.
6.      Jing Tian; Yang Yu; Yao Wang; Haoyi Li; Lujuan Yang; Baoan Du*; Gang Ma*, Tannic Acid-Induced Surface-Catalyzed Secondary Nucleation During the Amyloid Fibrillation of Hen Egg-White Lysozyme, International Journal of Molecular Sciences, 2018, 19 (12): 4009.
7.      Baohuan Jia; Ying Sun; Lujuan Yang; Yang Yu; Haoran Fan; Gang Ma*, A Structural Model of the Hierarchical Assembly of an Amyloid Nanosheet by an Infrared Probe Technique, Physical Chemistry Chemical Physics, 2018, 20 (43): 27261-27271.(Back Cover)
8.      Zhe Qin; Ying Sun; Baohuan Jia; Dan Wang; Yan Ma; Gang Ma*, Kinetic Mechanism of Thioflavin T Binding onto the Amyloid Fibril of Hen Egg White Lysozyme, Langmuir, 2017, 33 (22): 5398-5405.
9.      Haoyi Li; Yachao Gao; Chunxiao Li; Gang Ma*; Yanli Shang*; Ying Sun, A Comparative Study of the Antibacterial Mechanisms of Silver Ion and Silver Nanoparticles by Fourier Transform Infrared Spectroscopy, Vibrational Spectroscopy, 2016, 85: 112-121.
10.    Yachao Gao; Ye Zou; Yan Ma; Dan Wang; Ying Sun; Gang Ma*, Infrared Probe Technique Reveals a Millipede-Like Structure for a Beta(8-28) Amyloid Fibril, Langmuir, 2016, 32 (4): 937-946.
11.    Ye Zou; Gang Ma*, A New Criterion to Evaluate Water Vapor Interference in Protein Secondary Structural Analysis by FTIR Spectroscopy, International Journal of Molecular Sciences, 2014, 15 (6): 10018-10033.
12.    Ye Zou; Wenying Hao; Haoyi Li; Yachao Gao; Ying Sun; Gang Ma*, New Insight into Amyloid Fibril Formation of Hen Egg White Lysozyme Using a Two-Step Temperature-Dependent FTIR Approach, Journal of Physical Chemistry B, 2014, 118 (33): 9834-9843.
13.    Ye Zou; Yiyi Li; Wenying Hao; Xiaoqian Hu; Gang Ma*, Parallel Beta-Sheet Fibril and Antiparallel Beta-Sheet Oligomer: New Insights into Amyloid Formation of Hen Egg White Lysozyme under Heat and Acidic Condition from FTIR Spectroscopy, Journal of Physical Chemistry B, 2013, 117 (15): 4003-4013.
14.    Ying Sun; Ye Zou; Gang Ma*, A Convenient and Cost-Effective Fourier Transform Infrared (FTIR) Spectrometer Purging Setup for the Undergraduate Teaching Laboratory, Journal of Chemical Education, 2013, 90 (7): 950-951.
15.    Gang Ma*; Yiyi Li; Jun Dong; Ye Zou; Zhihui Zhang; Ying Sun, The Dynamic Nature of Incubation Solution after Cooling to Room Temperature in Amyloid Formation of Hen Egg White Lysozyme: An FTIR Assessment, Vibrational Spectroscopy, 2013, 64: 44-50.

1. 
   Prior Publications (*Corresponding Author):
   
   1. L. Fu, G. Ma, And E. C. Y. Yan* (2010) In Situ Misfolding Of Human Islet Amyloid Polypeptide At Interfaces Probed By Vibrational Sum Frequency Generation, J. Am. Chem. Soc. 132, 5405-5412.
   
   2. G. Ma, J. Liu, L. Fu, And E. C. Y. Yan* (2009) Probing Water And Biomolecules At The Air/Water Interface With A Broad-Bandwidth Vibrational Sum Frequency Generation Spectrometer From 3800 To 900 Cm^-1, Appl. Spectrosc. 63, 528-537.
   
   3. G. Ma, X. Chen, And H. C. Allen* (2007) Dangling OD Confined In A Langmuir Monolayer. J. Am. Chem. Soc. 129, 14053-14057.
   
   4. G. Ma And H. C. Allen* (2007) Condensing Effect Of Palmitic Acid On DPPC In Mixed Langmuir Monolayers. Langmuir 23, 589-597.
   
   5. G. Ma And H. C. Allen* (2006) Real-Time Investigation Of Lung Surfactant Respreading With Surface Vibrational Spectroscopy. Langmuir 22, 1267 - 11274.
   
   6. G. Ma And H. C. Allen* (2006) New Insights Into Lung Surfactant Monolayers Using Vibrational Sum Frequency Generation Spectroscopy. Photochem. Photobiol. 82, 1517-1529.
   
   7. G. Ma And H. C. Allen* (2006) DPPC Langmuir Monolayer At The Air-Water Interface: Probing The Tail And Head Groups By Vibrational Sum Frequency Generation Spectroscopy. Langmuir 22, 5341-5349.
   
   8. D. Liu, G. Ma And H. C. Allen* (2005) Adsorption Of 4-Picoline And Piperidine To The Hydrated SiO2 Surface: Probing The Surface Acidity With Vibrational Sum Frequency Generation Spectroscopy. Environ. Sci. Technol.  39, 2025-2032.
   
   9. D. Liu, G. Ma, M. Xu And H. C. Allen* (2005) Adsorption Of Ethylene Glycol Vapor On A-Al₂O₃ (0001) And Amorphous SiO₂ Surfaces: Observation Of Molecular Orientation And Surface Hydroxyl Groups As Sorption Sites. Environ. Sci. Technol.  39, 206-212.
   
   10. G. Ma And H. C. Allen* (2004) Handbook Of Spectroscopy, Volumes 1 And 2. Edited By Guenter Gauglitz (University Of Tuebingen) And Tuan Vo-Dinh (Oak Ridge National Laboratory). Wiley-VCH Verlag GmbH & Co. KGaA: Weinheim. 2003. 1168 Pp. J. Am. Chem. Soc.  126, 8859-8860.
   
   11. G. Ma, D. Liu And H. C. Allen* (2004) Piperidine Adsorption On Hydrated Alpha-Alumina (0001) Surface Studied By Vibrational Sum Frequency Generation Spectroscopy. Langmuir 20, 11620-11629.
   
   12. D. Liu, G. Ma, L. M. Levering And H. C. Allen* (2004) Vibrational Spectroscopy Of Aqueous Sodium Halide Solutions And Air-Liquid Interfaces: Observation Of Increased Interfacial Depth. J. Phys. Chem. B 108, 2252-2260.
   
   13. G. Ma And H. C. Allen* (2003) Surface Studies Of Aqueous Methanol Solutions By Vibrational Broad Bandwidth Sum Frequency Generation Spectroscopy. J. Phys. Chem. B 107, 6343-6349.
   
   14. G. Ma And H. C. Allen* (2002) Diffuse Reflection Broad Bandwidth Sum Frequency Generation From Particle Surfaces. J. Am. Chem. Soc.  124, 9374-9375.
   
   15. E. L. Hommel, G. Ma And H. C. Allen* (2001) Broadband Vibrational Sum Frequency Generation Spectroscopy Of A Liquid Surface. Anal. Sci.  17, 1325-1329.
   
   16. G. Ma, W. Yan, T. Hu, J. Chen, C. Yan, H. Gao, J. Wu* And G. Xu (1999) FTIR And EXAFS Investigations Of Microstructures Of Gold Solvent Extraction: Hydrogen Bonding Between Modifier And Au(CN)2. Phys. Chem. Chem. Phys.  1, 5215-5221.